Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity

Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity

Poly(ADP-ribose) glycohydrolase (PARG) is involved in different cellular processes including DNA repair. Here the authors reveal a role for PARG in regulating meiotic DNA double strand break induction and repair in Caenorhabditis elegans.

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Autores principales: Eva Janisiw, Marilina Raices, Fabiola Balmir, Luis F. Paulin, Antoine Baudrimont, Arndt von Haeseler, Judith L. Yanowitz, Verena Jantsch, Nicola Silva
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Q
Acceso en línea:https://doaj.org/article/6fbdd58c4ad94b98ba5e66e4807523fd
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spelling oai:doaj.org-article:6fbdd58c4ad94b98ba5e66e4807523fd2021-12-02T18:14:41ZPoly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity10.1038/s41467-020-18693-12041-1723https://doaj.org/article/6fbdd58c4ad94b98ba5e66e4807523fd2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18693-1https://doaj.org/toc/2041-1723Poly(ADP-ribose) glycohydrolase (PARG) is involved in different cellular processes including DNA repair. Here the authors reveal a role for PARG in regulating meiotic DNA double strand break induction and repair in Caenorhabditis elegans.Eva JanisiwMarilina RaicesFabiola BalmirLuis F. PaulinAntoine BaudrimontArndt von HaeselerJudith L. YanowitzVerena JantschNicola SilvaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eva Janisiw
Marilina Raices
Fabiola Balmir
Luis F. Paulin
Antoine Baudrimont
Arndt von Haeseler
Judith L. Yanowitz
Verena Jantsch
Nicola Silva
Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
description Poly(ADP-ribose) glycohydrolase (PARG) is involved in different cellular processes including DNA repair. Here the authors reveal a role for PARG in regulating meiotic DNA double strand break induction and repair in Caenorhabditis elegans.
format article
author Eva Janisiw
Marilina Raices
Fabiola Balmir
Luis F. Paulin
Antoine Baudrimont
Arndt von Haeseler
Judith L. Yanowitz
Verena Jantsch
Nicola Silva
author_facet Eva Janisiw
Marilina Raices
Fabiola Balmir
Luis F. Paulin
Antoine Baudrimont
Arndt von Haeseler
Judith L. Yanowitz
Verena Jantsch
Nicola Silva
author_sort Eva Janisiw
title Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
title_short Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
title_full Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
title_fullStr Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
title_full_unstemmed Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
title_sort poly(adp-ribose) glycohydrolase coordinates meiotic dna double-strand break induction and repair independent of its catalytic activity
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/6fbdd58c4ad94b98ba5e66e4807523fd
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AT marilinaraices polyadpriboseglycohydrolasecoordinatesmeioticdnadoublestrandbreakinductionandrepairindependentofitscatalyticactivity
AT fabiolabalmir polyadpriboseglycohydrolasecoordinatesmeioticdnadoublestrandbreakinductionandrepairindependentofitscatalyticactivity
AT luisfpaulin polyadpriboseglycohydrolasecoordinatesmeioticdnadoublestrandbreakinductionandrepairindependentofitscatalyticactivity
AT antoinebaudrimont polyadpriboseglycohydrolasecoordinatesmeioticdnadoublestrandbreakinductionandrepairindependentofitscatalyticactivity
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AT verenajantsch polyadpriboseglycohydrolasecoordinatesmeioticdnadoublestrandbreakinductionandrepairindependentofitscatalyticactivity
AT nicolasilva polyadpriboseglycohydrolasecoordinatesmeioticdnadoublestrandbreakinductionandrepairindependentofitscatalyticactivity
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