Neurovascular imaging with QUTE-CE MRI in APOE4 rats reveals early vascular abnormalities.

Neurovascular imaging with QUTE-CE MRI in APOE4 rats reveals early vascular abnormalities.

Cerebrovascular abnormality is linked to Alzheimer's disease and related dementias (ADRDs). ApoE-Ɛ4 (APOE4) is known to play a critical role in neurovascular dysfunction, however current medical imaging technologies are limited in quantification. This cross-sectional study tested the feasibilit...

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Main Authors: Joshua Leaston, Craig F Ferris, Praveen Kulkarni, Dharshan Chandramohan, Anne L van de Ven, Ju Qiao, Liam Timms, Jorge Sepulcre, Georges El Fakhri, Chao Ma, Marc D Normandin, Codi Gharagouzloo
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/6fd6878838654be6add5ef9afa96e68c
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https://doaj.org/article/6fd6878838654be6add5ef9afa96e68c

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