Ultrasensitive and high-efficiency screen of de novo low-frequency mutations by o2n-seq

Detection ofde novo, low frequency mutations is important for characterising heterogeneous cell populations, such as those found in cancer cell populations. Here the authors present o2n-seq, an ultrasensitive method with highly efficient data usage for detection of rare mutations.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kaile Wang, Shujuan Lai, Xiaoxu Yang, Tianqi Zhu, Xuemei Lu, Chung-I Wu, Jue Ruan
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/6fd788ebdd2d4aa9a1ab98de73353467
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!