Identification of critical amino acid residues in the regulatory N-terminal domain of PMEL
Abstract The pigment cell-specific protein PMEL forms a functional amyloid matrix in melanosomes onto which the pigment melanin is deposited. The amyloid core consists of a short proteolytic fragment, which we have termed the core-amyloid fragment (CAF) and perhaps additional parts of the protein, s...
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Main Authors: | , , , |
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Format: | article |
Language: | EN |
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Nature Portfolio
2021
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Online Access: | https://doaj.org/article/6fe1f58f16b744199acb7c25c9e073c8 |
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