Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival

Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival

Random-pattern skin flap is a vital technique frequently applied in reconstruction surgeries for its convenience and effectiveness in solving skin defects. However, ischemic necrosis, especially in the distal areas of the flap, still needs extra attention after surgery. Earlier evidence has suggeste...

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Bibliographic Details
Main Authors: Jingtao Jiang, Chengji Dong, Liang Zhai, Junsheng Lou, Jie Jin, Sheng Cheng, Zhuliu Chen, Xiaoshan Guo, Damu Lin, Jian Ding, Weiyang Gao
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
paeoniflorin
random skin flap
oxidative stress
apoptosis
angiogenesis
Nrf2/HO-1 signaling pathway
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/6fe4cfca01da4411b1d62807b690bc23
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https://doaj.org/article/6fe4cfca01da4411b1d62807b690bc23

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