Genomics and transcriptomics of the green mussel explain the durability of its byssus

Abstract Mussels, which occupy important positions in marine ecosystems, attach tightly to underwater substrates using a proteinaceous holdfast known as the byssus, which is tough, durable, and resistant to enzymatic degradation. Although various byssal proteins have been identified, the mechanisms...

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Main Authors:	Koji Inoue, Yuki Yoshioka, Hiroyuki Tanaka, Azusa Kinjo, Mieko Sassa, Ikuo Ueda, Chuya Shinzato, Atsushi Toyoda, Takehiko Itoh
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Medicine R Science Q
Online Access:	https://doaj.org/article/6fed99ff34d442bd8e5ab64743dd2e78
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spelling	oai:doaj.org-article:6fed99ff34d442bd8e5ab64743dd2e782021-12-02T13:17:56ZGenomics and transcriptomics of the green mussel explain the durability of its byssus10.1038/s41598-021-84948-62045-2322https://doaj.org/article/6fed99ff34d442bd8e5ab64743dd2e782021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84948-6https://doaj.org/toc/2045-2322Abstract Mussels, which occupy important positions in marine ecosystems, attach tightly to underwater substrates using a proteinaceous holdfast known as the byssus, which is tough, durable, and resistant to enzymatic degradation. Although various byssal proteins have been identified, the mechanisms by which it achieves such durability are unknown. Here we report comprehensive identification of genes involved in byssus formation through whole-genome and foot-specific transcriptomic analyses of the green mussel, Perna viridis. Interestingly, proteins encoded by highly expressed genes include proteinase inhibitors and defense proteins, including lysozyme and lectins, in addition to structural proteins and protein modification enzymes that probably catalyze polymerization and insolubilization. This assemblage of structural and protective molecules constitutes a multi-pronged strategy to render the byssus highly resistant to environmental insults.Koji InoueYuki YoshiokaHiroyuki TanakaAzusa KinjoMieko SassaIkuo UedaChuya ShinzatoAtsushi ToyodaTakehiko ItohNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Koji Inoue Yuki Yoshioka Hiroyuki Tanaka Azusa Kinjo Mieko Sassa Ikuo Ueda Chuya Shinzato Atsushi Toyoda Takehiko Itoh Genomics and transcriptomics of the green mussel explain the durability of its byssus
description	Abstract Mussels, which occupy important positions in marine ecosystems, attach tightly to underwater substrates using a proteinaceous holdfast known as the byssus, which is tough, durable, and resistant to enzymatic degradation. Although various byssal proteins have been identified, the mechanisms by which it achieves such durability are unknown. Here we report comprehensive identification of genes involved in byssus formation through whole-genome and foot-specific transcriptomic analyses of the green mussel, Perna viridis. Interestingly, proteins encoded by highly expressed genes include proteinase inhibitors and defense proteins, including lysozyme and lectins, in addition to structural proteins and protein modification enzymes that probably catalyze polymerization and insolubilization. This assemblage of structural and protective molecules constitutes a multi-pronged strategy to render the byssus highly resistant to environmental insults.
format	article
author	Koji Inoue Yuki Yoshioka Hiroyuki Tanaka Azusa Kinjo Mieko Sassa Ikuo Ueda Chuya Shinzato Atsushi Toyoda Takehiko Itoh
author_facet	Koji Inoue Yuki Yoshioka Hiroyuki Tanaka Azusa Kinjo Mieko Sassa Ikuo Ueda Chuya Shinzato Atsushi Toyoda Takehiko Itoh
author_sort	Koji Inoue
title	Genomics and transcriptomics of the green mussel explain the durability of its byssus
title_short	Genomics and transcriptomics of the green mussel explain the durability of its byssus
title_full	Genomics and transcriptomics of the green mussel explain the durability of its byssus
title_fullStr	Genomics and transcriptomics of the green mussel explain the durability of its byssus
title_full_unstemmed	Genomics and transcriptomics of the green mussel explain the durability of its byssus
title_sort	genomics and transcriptomics of the green mussel explain the durability of its byssus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6fed99ff34d442bd8e5ab64743dd2e78
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Genomics and transcriptomics of the green mussel explain the durability of its byssus

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