Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis

The 3-thiazolidine ring, a pharmaceutically interesting cyclic structural element found e.g. in some antibiotics, is hard to obtain via currently used approaches. Here, the authors developed a straightforward method to efficiently synthesize a variety of defined, pure 3-thiazolidines.

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Autores principales: Nadine Zumbrägel, Christian Merten, Stefan M. Huber, Harald Gröger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/70159b5ac5fd47009fa14f6aef22e6b2
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