Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis

The 3-thiazolidine ring, a pharmaceutically interesting cyclic structural element found e.g. in some antibiotics, is hard to obtain via currently used approaches. Here, the authors developed a straightforward method to efficiently synthesize a variety of defined, pure 3-thiazolidines.

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Autores principales:	Nadine Zumbrägel, Christian Merten, Stefan M. Huber, Harald Gröger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/70159b5ac5fd47009fa14f6aef22e6b2
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spelling	oai:doaj.org-article:70159b5ac5fd47009fa14f6aef22e6b22021-12-02T16:49:51ZEnantioselective reduction of sulfur-containing cyclic imines through biocatalysis10.1038/s41467-018-03841-52041-1723https://doaj.org/article/70159b5ac5fd47009fa14f6aef22e6b22018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03841-5https://doaj.org/toc/2041-1723The 3-thiazolidine ring, a pharmaceutically interesting cyclic structural element found e.g. in some antibiotics, is hard to obtain via currently used approaches. Here, the authors developed a straightforward method to efficiently synthesize a variety of defined, pure 3-thiazolidines.Nadine ZumbrägelChristian MertenStefan M. HuberHarald GrögerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nadine Zumbrägel Christian Merten Stefan M. Huber Harald Gröger Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
description	The 3-thiazolidine ring, a pharmaceutically interesting cyclic structural element found e.g. in some antibiotics, is hard to obtain via currently used approaches. Here, the authors developed a straightforward method to efficiently synthesize a variety of defined, pure 3-thiazolidines.
format	article
author	Nadine Zumbrägel Christian Merten Stefan M. Huber Harald Gröger
author_facet	Nadine Zumbrägel Christian Merten Stefan M. Huber Harald Gröger
author_sort	Nadine Zumbrägel
title	Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
title_short	Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
title_full	Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
title_fullStr	Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
title_full_unstemmed	Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
title_sort	enantioselective reduction of sulfur-containing cyclic imines through biocatalysis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/70159b5ac5fd47009fa14f6aef22e6b2
work_keys_str_mv	AT nadinezumbragel enantioselectivereductionofsulfurcontainingcycliciminesthroughbiocatalysis AT christianmerten enantioselectivereductionofsulfurcontainingcycliciminesthroughbiocatalysis AT stefanmhuber enantioselectivereductionofsulfurcontainingcycliciminesthroughbiocatalysis AT haraldgroger enantioselectivereductionofsulfurcontainingcycliciminesthroughbiocatalysis
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Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis

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