Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative
Reducing aerobic ethanol production, a phenomenon referred to as the Crabtree effect, may open up new perspectives for using yeast as a cell factory. Here, the authors turn the Crabtree-positive yeast into Crabtree negative by combined engineering of cytosolic acetyl-CoA metabolism and mutating the...
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Autores principales: | Zongjie Dai, Mingtao Huang, Yun Chen, Verena Siewers, Jens Nielsen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/7016397e466f4d609b444d494707624d |
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