miR-519d downregulates LEP expression to inhibit preeclampsia development

The purpose of the current study was to characterize role of microRNA (miR)-519d in trophoblast cells and preeclampsia (PE) development and its potential underlying mechanism. Regulation of leptin (LEP) by miR-519d was verified using a dual-luciferase reporter gene assay. Loss- and gain-of-function...

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Détails bibliographiques
Auteurs principaux: Cai Hairui, Li Dongmei, Wu Jun, Shi Chunbo
Format: article
Langue:EN
Publié: De Gruyter 2021
Sujets:
R
Accès en ligne:https://doaj.org/article/7043e52e408e467abea727c57fb9262f
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