Network-based in silico drug efficacy screening
Attempts to predict novel use for existing drugs rarely consider information on the impact on the genes perturbed in a given disease. Here, the authors present a novel network-based drug-disease proximity measure that provides insight on gene specific therapeutic effect of drugs and may facilitate d...
Enregistré dans:
Auteurs principaux: | Emre Guney, Jörg Menche, Marc Vidal, Albert-László Barábasi |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/7056300b2e664a3daefdec33e6639c3e |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Network-based approach to prediction and population-based validation of in silico drug repurposing
par: Feixiong Cheng, et autres
Publié: (2018) -
Network-based prediction of drug combinations
par: Feixiong Cheng, et autres
Publié: (2019) -
Publisher Correction: Network-based prediction of drug combinations
par: Feixiong Cheng, et autres
Publié: (2019) -
Integrating personalized gene expression profiles into predictive disease-associated gene pools
par: Jörg Menche, et autres
Publié: (2017) -
A genome-wide positioning systems network algorithm for in silico drug repurposing
par: Feixiong Cheng, et autres
Publié: (2019)