The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy

The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy

Background: Malaria during pregnancy is a major contributor to the global burden of adverse birth outcomes including fetal growth restriction, preterm birth, and fetal loss. Recent evidence supports a role for angiogenic dysregulation and perturbations to placental vascular development in the pathob...

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Autores principales: Vanessa Tran, Andrea M. Weckman, Valerie M. Crowley, Lindsay S. Cahill, Kathleen Zhong, Ana Cabrera, Robyn E. Elphinstone, Victoria Pearce, Mwayiwawo Madanitsa, Linda Kalilani-Phiri, Victor Mwapasa, Carole Khairallah, Andrea L. Conroy, Feiko O. ter Kuile, John G. Sled, Kevin C. Kain
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Malaria
pregnancy
angiopoietin-Tie2
placental vasculature
angiopoietin-1
Medicine
R
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/70589bcf3d034d399a3578776efe1f17
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https://doaj.org/article/70589bcf3d034d399a3578776efe1f17

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