Morphological and mechanical characterization of bone phenotypes in the Amish G610C murine model of osteogenesis imperfecta.

Osteogenesis imperfecta (OI) is a hereditary bone disease where gene mutations affect Type I collagen formation resulting in osteopenia and increased fracture risk. There are several established mouse models of OI, but some are severe and result in spontaneous fractures or early animal death. The Am...

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Autores principales: Rachel Kohler, Carli A Tastad, Amy Creecy, Joseph M Wallace
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/705e950b3cc74900a0ef6792bb9987ac
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