In oxygen-deprived tumor cells ERp57 provides radioprotection and ensures proliferation via c-Myc, PLK1 and the AKT pathway

Abstract The disulfide isomerase ERp57, originally found in the endoplasmic reticulum, is located in multiple cellular compartments, participates in diverse cell functions and interacts with a huge network of binding partners. It was recently suggested as an attractive new target for cancer therapy...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tobias Ocklenburg, Fabian Neumann, Alexandra Wolf, Julia Vogel, Kirsten Göpelt, Melanie Baumann, Jennifer Baumann, Philip Kranz, Eric Metzen, Ulf Brockmeier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/70c99fc6b9384a9d8053fe7ddefd8962
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!