Aurora A drives early signalling and vesicle dynamics during T-cell activation

Aurora A drives early signalling and vesicle dynamics during T-cell activation

Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.

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Auteurs principaux: Noelia Blas-Rus, Eugenio Bustos-Morán, Ignacio Pérez de Castro, Guillermo de Cárcer, Aldo Borroto, Emilio Camafeita, Inmaculada Jorge, Jesús Vázquez, Balbino Alarcón, Marcos Malumbres, Noa B. Martín-Cófreces, Francisco Sánchez-Madrid
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/70cde4b8e22c4dcfa69bb2d3c104caa9
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Internet

https://doaj.org/article/70cde4b8e22c4dcfa69bb2d3c104caa9

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