Synergistic alterations in the multilevel chromatin structure anchor dysregulated genes in small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive form of lung cancer that uniquely changes the chromosomal structure, although the basis of aberrant gene expression in SCLC remains largely unclear. Topologically associated domains (TADs) are structural and functional units of the human genome. Genetic...

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Autores principales: Dan Guo, Qiu Xie, Shuai Jiang, Ting Xie, Yaru Li, Xin Huang, Fangyuan Li, Tingting Wang, Jian Sun, Anqi Wang, Zixin Zhang, Hao Li, Xiaochen Bo, Hebing Chen, Zhiyong Liang
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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TAD
Acceso en línea:https://doaj.org/article/70dd559a86354770ae7cc3d1fa802cad
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