TNF-α mediated increase of HIF-1α inhibits VASP expression, which reduces alveolar-capillary barrier function during acute lung injury (ALI).

TNF-α mediated increase of HIF-1α inhibits VASP expression, which reduces alveolar-capillary barrier function during acute lung injury (ALI).

Acute lung injury (ALI) is an inflammatory disorder associated with reduced alveolar-capillary barrier function and increased pulmonary vascular permeability. Vasodilator-stimulated phosphoprotein (VASP) is widely associated with all types of modulations of cytoskeleton rearrangement-dependent cellu...

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Autores principales: Mengjie Tang, Yihao Tian, Doulin Li, Jiawei Lv, Qun Li, Changchun Kuang, Pengchao Hu, Ying Wang, Jing Wang, Ke Su, Lei Wei
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/70e9ae465d7948a2a67355d07d554f84
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https://doaj.org/article/70e9ae465d7948a2a67355d07d554f84

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