TNF-α mediated increase of HIF-1α inhibits VASP expression, which reduces alveolar-capillary barrier function during acute lung injury (ALI).
Acute lung injury (ALI) is an inflammatory disorder associated with reduced alveolar-capillary barrier function and increased pulmonary vascular permeability. Vasodilator-stimulated phosphoprotein (VASP) is widely associated with all types of modulations of cytoskeleton rearrangement-dependent cellu...
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Autores principales: | Mengjie Tang, Yihao Tian, Doulin Li, Jiawei Lv, Qun Li, Changchun Kuang, Pengchao Hu, Ying Wang, Jing Wang, Ke Su, Lei Wei |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/70e9ae465d7948a2a67355d07d554f84 |
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