Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway.

Trehalose 6,6'-dimycolate (TDM), a cord factor of Mycobacterium tuberculosis (Mtb), is an important regulator of immune responses during Mtb infections. Macrophages recognize TDM through the Mincle receptor and initiate TDM-induced inflammatory responses, leading to lung granuloma formation. Al...

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Autores principales: Wook-Bin Lee, Ji-Seon Kang, Ji-Jing Yan, Myeong Sup Lee, Bo-Young Jeon, Sang-Nae Cho, Young-Joon Kim
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/70f3297d06ef4802bd6884ffb8bc6a16
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