Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and identifying toxin variants.
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Nature Portfolio
2021
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oai:doaj.org-article:70fd425450ac4e308cdcc1e3850305632021-12-02T13:14:48ZSpatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae10.1038/s41467-021-21870-52041-1723https://doaj.org/article/70fd425450ac4e308cdcc1e3850305632021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21870-5https://doaj.org/toc/2041-1723Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and identifying toxin variants.Robert C. WillThandavarayan RamamurthyNaresh Chand SharmaBalaji VeeraraghavanLucky SangalPradeep HaldarAgila Kumari PragasamKarthick VasudevanDhirendra KumarBhabatosh DasEva HeinzVyacheslav MelnikovStephen BakerVartul SangalGordon DouganAnkur MutrejaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021) |
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Science Q Robert C. Will Thandavarayan Ramamurthy Naresh Chand Sharma Balaji Veeraraghavan Lucky Sangal Pradeep Haldar Agila Kumari Pragasam Karthick Vasudevan Dhirendra Kumar Bhabatosh Das Eva Heinz Vyacheslav Melnikov Stephen Baker Vartul Sangal Gordon Dougan Ankur Mutreja Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae |
description |
Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and identifying toxin variants. |
format |
article |
author |
Robert C. Will Thandavarayan Ramamurthy Naresh Chand Sharma Balaji Veeraraghavan Lucky Sangal Pradeep Haldar Agila Kumari Pragasam Karthick Vasudevan Dhirendra Kumar Bhabatosh Das Eva Heinz Vyacheslav Melnikov Stephen Baker Vartul Sangal Gordon Dougan Ankur Mutreja |
author_facet |
Robert C. Will Thandavarayan Ramamurthy Naresh Chand Sharma Balaji Veeraraghavan Lucky Sangal Pradeep Haldar Agila Kumari Pragasam Karthick Vasudevan Dhirendra Kumar Bhabatosh Das Eva Heinz Vyacheslav Melnikov Stephen Baker Vartul Sangal Gordon Dougan Ankur Mutreja |
author_sort |
Robert C. Will |
title |
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae |
title_short |
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae |
title_full |
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae |
title_fullStr |
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae |
title_full_unstemmed |
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae |
title_sort |
spatiotemporal persistence of multiple, diverse clades and toxins of corynebacterium diphtheriae |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/70fd425450ac4e308cdcc1e385030563 |
work_keys_str_mv |
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1718393390685487104 |