Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae

Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and identifying toxin variants.

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Autores principales: Robert C. Will, Thandavarayan Ramamurthy, Naresh Chand Sharma, Balaji Veeraraghavan, Lucky Sangal, Pradeep Haldar, Agila Kumari Pragasam, Karthick Vasudevan, Dhirendra Kumar, Bhabatosh Das, Eva Heinz, Vyacheslav Melnikov, Stephen Baker, Vartul Sangal, Gordon Dougan, Ankur Mutreja
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Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:70fd425450ac4e308cdcc1e3850305632021-12-02T13:14:48ZSpatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae10.1038/s41467-021-21870-52041-1723https://doaj.org/article/70fd425450ac4e308cdcc1e3850305632021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21870-5https://doaj.org/toc/2041-1723Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and identifying toxin variants.Robert C. WillThandavarayan RamamurthyNaresh Chand SharmaBalaji VeeraraghavanLucky SangalPradeep HaldarAgila Kumari PragasamKarthick VasudevanDhirendra KumarBhabatosh DasEva HeinzVyacheslav MelnikovStephen BakerVartul SangalGordon DouganAnkur MutrejaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Robert C. Will
Thandavarayan Ramamurthy
Naresh Chand Sharma
Balaji Veeraraghavan
Lucky Sangal
Pradeep Haldar
Agila Kumari Pragasam
Karthick Vasudevan
Dhirendra Kumar
Bhabatosh Das
Eva Heinz
Vyacheslav Melnikov
Stephen Baker
Vartul Sangal
Gordon Dougan
Ankur Mutreja
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
description Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and identifying toxin variants.
format article
author Robert C. Will
Thandavarayan Ramamurthy
Naresh Chand Sharma
Balaji Veeraraghavan
Lucky Sangal
Pradeep Haldar
Agila Kumari Pragasam
Karthick Vasudevan
Dhirendra Kumar
Bhabatosh Das
Eva Heinz
Vyacheslav Melnikov
Stephen Baker
Vartul Sangal
Gordon Dougan
Ankur Mutreja
author_facet Robert C. Will
Thandavarayan Ramamurthy
Naresh Chand Sharma
Balaji Veeraraghavan
Lucky Sangal
Pradeep Haldar
Agila Kumari Pragasam
Karthick Vasudevan
Dhirendra Kumar
Bhabatosh Das
Eva Heinz
Vyacheslav Melnikov
Stephen Baker
Vartul Sangal
Gordon Dougan
Ankur Mutreja
author_sort Robert C. Will
title Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
title_short Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
title_full Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
title_fullStr Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
title_full_unstemmed Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
title_sort spatiotemporal persistence of multiple, diverse clades and toxins of corynebacterium diphtheriae
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/70fd425450ac4e308cdcc1e385030563
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