Genetic Validation of<italic toggle="yes"> Leishmania donovani</italic> Lysyl-tRNA Synthetase Shows that It Is Indispensable for Parasite Growth and Infectivity
ABSTRACT Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis. Increasing resistance and severe side effects of existing drugs have led to the need to identify new chemotherapeutic targets. Aminoacyl-tRNA synthetases (aaRSs) are ubiquitous and are required for protein synth...
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Main Authors: | , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Subjects: | |
Online Access: | https://doaj.org/article/7101a03993594215a882b8c8217e2998 |
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