Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter

Abstract Dopamine transporter (DAT) has been shown to accumulate in filopodia in neurons and non-neuronal cells. To examine the mechanisms of DAT filopodial targeting, we used quantitative live-cell fluorescence microscopy, and compared the effects of the DAT inhibitor cocaine and its fluorescent an...

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Autores principales: Shiqi Ma, Mary H. Cheng, Daryl A. Guthrie, Amy H. Newman, Ivet Bahar, Alexander Sorkin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/712ba815e1554d59aab2ad3df60977dc
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