Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter
Abstract Dopamine transporter (DAT) has been shown to accumulate in filopodia in neurons and non-neuronal cells. To examine the mechanisms of DAT filopodial targeting, we used quantitative live-cell fluorescence microscopy, and compared the effects of the DAT inhibitor cocaine and its fluorescent an...
Guardado en:
Autores principales: | Shiqi Ma, Mary H. Cheng, Daryl A. Guthrie, Amy H. Newman, Ivet Bahar, Alexander Sorkin |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/712ba815e1554d59aab2ad3df60977dc |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Substrate-induced conformational dynamics of the dopamine transporter
por: Anne Kathrine Nielsen, et al.
Publicado: (2019) -
Membrane potential shapes regulation of dopamine transporter trafficking at the plasma membrane
por: Ben D. Richardson, et al.
Publicado: (2016) -
Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
por: Mark D. Condon, et al.
Publicado: (2019) -
Dopamine Transporter SPECT Imaging in Corticobasal Syndrome.
por: Roberto Cilia, et al.
Publicado: (2011) -
Dynamic control of the dopamine transporter in neurotransmission and homeostasis
por: Mengfei Bu, et al.
Publicado: (2021)