Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses

Abstract Enterovirus A71 (EV-A71) infection can induce encephalitis, which causes death or long-term neurological sequelae, especially in young children. Using a murine infection model, we searched for anti-EV-A71 agents, because effective therapies are not available to control fatal infection. In E...

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Autores principales: Yu-Wen Lin, Li-Chiu Wang, Chien-Kuo Lee, Shun-Hua Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7142f68ce92d485c825b4e26108d7e61
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