Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

The fish-hunting marine cone snail Conus geographus uses a specialized venom insulin to induce hypoglycemic shock in its prey. We recently showed that this venom insulin, Con-Ins G1, has unique characteristics relevant to the design of new insulin therapeutics. Here, we show that fish-hunting cone s...

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Détails bibliographiques
Auteurs principaux: Peter Ahorukomeye, Maria M Disotuar, Joanna Gajewiak, Santhosh Karanth, Maren Watkins, Samuel D Robinson, Paula Flórez Salcedo, Nicholas A Smith, Brian J Smith, Amnon Schlegel, Briony E Forbes, Baldomero Olivera, Danny Hung-Chieh Chou, Helena Safavi-Hemami
Format: article
Langue:EN
Publié: eLife Sciences Publications Ltd 2019
Sujets:
cone snail
venom
insulin
hypoglycemic shock
prey capture
diabetes
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/71443f02920a4c85a8dd87031b11da69
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Internet

https://doaj.org/article/71443f02920a4c85a8dd87031b11da69

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