HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.

QR Code

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.

<h4>Background</h4>It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead to long-term ART-free HIV remission or cure. As a result, we studied 2 individuals recruited from a pre-exposure prophylaxis (PrEP) program who started prophylactic ART an estimated 10...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Timothy J Henrich, Hiroyu Hatano, Oliver Bacon, Louise E Hogan, Rachel Rutishauser, Alison Hill, Mary F Kearney, Elizabeth M Anderson, Susan P Buchbinder, Stephanie E Cohen, Mohamed Abdel-Mohsen, Christopher W Pohlmeyer, Remi Fromentin, Rebecca Hoh, Albert Y Liu, Joseph M McCune, Jonathan Spindler, Kelly Metcalf-Pate, Kristen S Hobbs, Cassandra Thanh, Erica A Gibson, Daniel R Kuritzkes, Robert F Siliciano, Richard W Price, Douglas D Richman, Nicolas Chomont, Janet D Siliciano, John W Mellors, Steven A Yukl, Joel N Blankson, Teri Liegler, Steven G Deeks
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2017
Sujets:	Medicine R
Accès en ligne:	https://doaj.org/article/7146700700d742c7a0dd1a56e69b9226
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals
par: Rémi Fromentin, et autres
Publié: (2019)

HIV-1 Genomes Are Enriched in Memory CD4 <sup>+</sup> T-Cells with Short Half-Lives
par: Vincent Morcilla, et autres
Publié: (2021)

Nonhuman primate models for HIV cure research.
par: Cristian Apetrei, et autres
Publié: (2012)

The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency
par: Guillaume Mousseau, et autres
Publié: (2015)

Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART
par: Pierre Gantner, et autres
Publié: (2020)

Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy.
par: Mary F Kearney, et autres
Publié: (2014)

HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.
par: Sergio Serrano-Villar, et autres
Publié: (2014)

Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivo.
par: Mohamed Abdel-Mohsen, et autres
Publié: (2014)

Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30.
par: Louise E Hogan, et autres
Publié: (2018)

HIV-1 vaccine-induced T-cell responses cluster in epitope hotspots that differ from those induced in natural infection with HIV-1.
par: Tomer Hertz, et autres
Publié: (2013)

Early Emergence and Long-Term Persistence of HIV-Infected T-Cell Clones in Children
par: Michael J. Bale, et autres
Publié: (2021)

Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration.
par: Faroudy Boufassa, et autres
Publié: (2014)

Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations
par: Yuta Hikichi, et autres
Publié: (2021)

HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon.
par: Michael A Chattergoon, et autres
Publié: (2014)

Clustering of HIV Patients in Ethiopia
par: Biressaw W, et autres
Publié: (2021)

TB/HIV: A Clinical Manual
par: Weber, Martin W.

HIV treatment as prevention: optimising the impact of expanded HIV treatment programmes.
par: Wim Delva, et autres
Publié: (2012)

Effect of HIV‐1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction
par: Anjali B. Thakkar, et autres
Publié: (2021)

HIV Inhibition by Lactobacilli: Easier in a Test Tube Than in Real Life
par: Steven S. Witkin, et autres
Publié: (2015)

Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities
par: Rosiris León-Rivera, et autres
Publié: (2020)

Uncontrolled Hypertension amongst People Living with HIV on Antiretroviral Therapy at an Urban HIV Clinic in Swaziland
par: O. Jimoh, et autres
Publié: (2017)

Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.
par: Lina Josefsson, et autres
Publié: (2013)

Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda
par: Mary Kate Grabowski, et autres
Publié: (2020)

HIV and smoking: associated risks and prevention strategies
par: Kariuki W, et autres
Publié: (2015)

Performance of rapid point-of-care and laboratory tests for acute and established HIV infection in San Francisco.
par: Christopher D Pilcher, et autres
Publié: (2013)

HIV medicine
Publié: (1999)

Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.
par: Hélène C F Côté, et autres
Publié: (2012)

HIV, vascular and aging injuries in the brain of clinically stable HIV-infected adults: a (1)H MRS study.
par: Lucette A Cysique, et autres
Publié: (2013)

Mortality of HIV-infected patients starting antiretroviral therapy in sub-Saharan Africa: comparison with HIV-unrelated mortality.
par: Martin W G Brinkhof, et autres
Publié: (2009)

Modeling HIV vaccines in Brazil: assessing the impact of a future HIV vaccine on reducing new infections, mortality and number of people receiving ARV.
par: Maria Goretti P Fonseca, et autres
Publié: (2010)

Performance of risk-based criteria for targeting acute HIV screening in San Francisco.
par: Shelley N Facente, et autres
Publié: (2011)

Novel mechanisms of central nervous system damage in HIV infection
par: Joy E Hazleton, et autres
Publié: (2010)

Mother-to-Child Transmission of HIV and Its Predictors Among HIV-Exposed Infants at an Outpatient Clinic for HIV/AIDS in Vietnam
par: Nguyen RN, et autres
Publié: (2020)

Erosion of tropical bird diversity over a century is influenced by abundance, diet and subtle climatic tolerances
par: Jenna R. Curtis, et autres
Publié: (2021)

Attitudes of Indian HIV Clinicians Toward Depression in People Living with HIV
par: Brian T. Chan, et autres
Publié: (2017)

Convergent Evolution of HLA-C Downmodulation in HIV-1 and HIV-2
par: Kristina Hopfensperger, et autres
Publié: (2020)

Effect of HIV Envelope Vaccination on the Subsequent Antibody Response to HIV Infection
par: Zanele Ditse, et autres
Publié: (2020)

S-Equol mitigates motivational deficits and dysregulation associated with HIV-1
par: Kristen A. McLaurin, et autres
Publié: (2021)

Clinical epidemiology of bocavirus, rhinovirus, two polyomaviruses and four coronaviruses in HIV-infected and HIV-uninfected South African children.
par: Marta C Nunes, et autres
Publié: (2014)

Access to antiretroviral therapy among HIV/AIDS patients in Chiang Mai province, Thailand
par: Himakalasa W, et autres
Publié: (2013)