The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency

por Guillaume Mousseau, Cari F. Kessing, Rémi Fromentin, Lydie Trautmann, Nicolas Chomont, Susana T. Valente
Publicado 2015

Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

por Pierre Gantner, Amélie Pagliuzza, Marion Pardons, Moti Ramgopal, Jean-Pierre Routy, Rémi Fromentin, Nicolas Chomont
Publicado 2020

In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia

por Basiel Cole, Laurens Lambrechts, Pierre Gantner, Ytse Noppe, Noah Bonine, Wojciech Witkowski, Lennie Chen, Sarah Palmer, James I. Mullins, Nicolas Chomont, Marion Pardons, Linos Vandekerckhove
Publicado 2021

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals

por Rémi Fromentin, Sandrina DaFonseca, Cecilia T. Costiniuk, Mohamed El-Far, Francesco Andrea Procopio, Frederick M. Hecht, Rebecca Hoh, Steven G. Deeks, Daria J. Hazuda, Sharon R. Lewin, Jean-Pierre Routy, Rafick-Pierre Sékaly, Nicolas Chomont
Publicado 2019

IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cells

por Tomas Raul Wiche Salinas, Annie Gosselin, Laurence Raymond Marchand, Etiene Moreira Gabriel, Olivier Tastet, Jean-Philippe Goulet, Yuwei Zhang, Dragos Vlad, Hanane Touil, Jean-Pierre Routy, Mariana G. Bego, Mohamed El-Far, Nicolas Chomont, Alan L. Landay, Éric A. Cohen, Cécile Tremblay, Petronela Ancuta
Publicado 2021

Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART.

por Maria Pino, Susan Pereira Ribeiro, Amélie Pagliuzza, Khader Ghneim, Anum Khan, Emily Ryan, Justin L Harper, Colin T King, Sarah Welbourn, Luca Micci, Sol Aldrete, Keith A Delman, Theron Stuart, Michael Lowe, Jason M Brenchley, Cynthia A Derdeyn, Kirk Easley, Rafick P Sekaly, Nicolas Chomont, Mirko Paiardini, Vincent C Marconi
Publicado 2021

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.

por Timothy J Henrich, Hiroyu Hatano, Oliver Bacon, Louise E Hogan, Rachel Rutishauser, Alison Hill, Mary F Kearney, Elizabeth M Anderson, Susan P Buchbinder, Stephanie E Cohen, Mohamed Abdel-Mohsen, Christopher W Pohlmeyer, Remi Fromentin, Rebecca Hoh, Albert Y Liu, Joseph M McCune, Jonathan Spindler, Kelly Metcalf-Pate, Kristen S Hobbs, Cassandra Thanh, Erica A Gibson, Daniel R Kuritzkes, Robert F Siliciano, Richard W Price, Douglas D Richman, Nicolas Chomont, Janet D Siliciano, John W Mellors, Steven A Yukl, Joel N Blankson, Teri Liegler, Steven G Deeks
Publicado 2017