PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals

por Rémi Fromentin, Sandrina DaFonseca, Cecilia T. Costiniuk, Mohamed El-Far, Francesco Andrea Procopio, Frederick M. Hecht, Rebecca Hoh, Steven G. Deeks, Daria J. Hazuda, Sharon R. Lewin, Jean-Pierre Routy, Rafick-Pierre Sékaly, Nicolas Chomont
Publicado 2019

Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance

por Mohamed Fareh, Wei Zhao, Wenxin Hu, Joshua M. L. Casan, Amit Kumar, Jori Symons, Jennifer M. Zerbato, Danielle Fong, Ilia Voskoboinik, Paul G. Ekert, Rajeev Rudraraju, Damian F. J. Purcell, Sharon R. Lewin, Joseph A. Trapani
Publicado 2021

Broad activation of latent HIV-1 in vivo

por Kirston Barton, Bonnie Hiener, Anni Winckelmann, Thomas Aagaard Rasmussen, Wei Shao, Karen Byth, Robert Lanfear, Ajantha Solomon, James McMahon, Sean Harrington, Maria Buzon, Mathias Lichterfeld, Paul W. Denton, Rikke Olesen, Lars Østergaard, Martin Tolstrup, Sharon R. Lewin, Ole Schmeltz Søgaard, Sarah Palmer
Publicado 2016

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

por Eunice E. To, Ross Vlahos, Raymond Luong, Michelle L. Halls, Patrick C. Reading, Paul T. King, Christopher Chan, Grant R. Drummond, Christopher G. Sobey, Brad R. S. Broughton, Malcolm R. Starkey, Renee van der Sluis, Sharon R. Lewin, Steven Bozinovski, Luke A. J. O’Neill, Tim Quach, Christopher J. H. Porter, Doug A. Brooks, John J. O’Leary, Stavros Selemidis
Publicado 2017

Consensus statement on the role of health systems in advancing the long-term well-being of people living with HIV

por Jeffrey V. Lazarus, Kelly Safreed-Harmon, Adeeba Kamarulzaman, Jane Anderson, Ricardo Baptista Leite, Georg Behrens, Linda-Gail Bekker, Sanjay Bhagani, Darren Brown, Graham Brown, Susan Buchbinder, Carlos Caceres, Pedro E. Cahn, Patrizia Carrieri, Georgina Caswell, Graham S. Cooke, Antonella d’Arminio Monforte, Nikos Dedes, Julia del Amo, Richard Elliott, Wafaa M. El-Sadr, María José Fuster-Ruiz de Apodaca, Giovanni Guaraldi, Tim Hallett, Richard Harding, Margaret Hellard, Shabbar Jaffar, Meaghan Kall, Marina Klein, Sharon R. Lewin, Ken Mayer, Jose A. Pérez-Molina, Doreen Moraa, Denise Naniche, Denis Nash, Teymur Noori, Anton Pozniak, Reena Rajasuriar, Peter Reiss, Nesrine Rizk, Jürgen Rockstroh, Diana Romero, Caroline Sabin, David Serwadda, Laura Waters
Publicado 2021