Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis

Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis

Abstract Autotaxin (ATX) is a secreted enzyme metabolized by liver sinusoidal endothelial cells that has been associated with liver fibrosis. We evaluated serum ATX values in 128 treatment-naïve, histologically assessed primary biliary cholangitis (PBC) patients and 80 healthy controls for compariso...

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Main Authors: Satoru Joshita, Takeji Umemura, Yoko Usami, Yuki Yamashita, Gary L. Norman, Ayumi Sugiura, Tomoo Yamazaki, Naoyuki Fujimori, Takefumi Kimura, Akihiro Matsumoto, Koji Igarashi, Kaname Yoshizawa, Masao Ota, Eiji Tanaka
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/715988f2566c47be81b9f75420628d74
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https://doaj.org/article/715988f2566c47be81b9f75420628d74

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