Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death

Many forms of autoimmune disorder involve abnormal T cell functions, but how this versatility is achieved is not fully clear. Here the authors show that Sharpin-deficient Treg cells induce the death of local keratinocytes via multiple programmed cell death and innate inflammation to cause skin infla...

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Autores principales: Katsuhiro Sasaki, Ai Himeno, Tomoko Nakagawa, Yoshiteru Sasaki, Hiroshi Kiyonari, Kazuhiro Iwai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/716b05e17f3c43fa880e9ce7ddca92ca
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