Huntingtin-Interacting Protein 1 Promotes Vpr-Induced G2 Arrest and HIV-1 Infection in Macrophages

Human immunodeficiency virus type 1 (HIV-1) modulates the host cell cycle. The HIV-1 accessory protein Vpr arrests the cell cycle at the G2 phase in dividing cells, and the ability of Vpr to induce G2 arrest is well conserved among primate lentiviruses. Additionally, Vpr-mediated G2 arrest likely co...

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Autores principales: Tomoyuki Murakami, Ryosuke Matsuura, Nopporn Chutiwitoonchai, Masami Takei, Yoko Aida
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Vpr
Acceso en línea:https://doaj.org/article/718ccc91f4b649698b4b464a00452c01
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