<italic toggle="yes">In Vivo</italic> Emergence of a Novel Protease Inhibitor Resistance Signature in HIV-1 Matrix

ABSTRACT Protease inhibitors (PIs) are the second- and last-line therapy for the majority of HIV-infected patients worldwide. Only around 20% of individuals who fail PI regimens develop major resistance mutations in protease. We sought to explore the role of mutations in gag-pro genotypic and phenot...

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Auteurs principaux: Rawlings Datir, Steven Kemp, Kate El Bouzidi, Petra Mlchocova, Richard Goldstein, Judy Breuer, Greg J. Towers, Clare Jolly, Miguel E. Quiñones-Mateu, Patrick S. Dakum, Nicaise Ndembi, Ravindra K. Gupta
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
Sujets:
HIV
Accès en ligne:https://doaj.org/article/7199b87aeca649fba51303efebde939d
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