Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants.

Natural products represent a significant reservoir of unexplored chemical diversity for early-stage drug discovery. The identification of lead compounds of natural origin would benefit from therapeutically relevant bioassays capable of facilitating the isolation of bioactive molecules from multi-con...

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Autores principales: Alexander D Crawford, Sandra Liekens, Appolinary R Kamuhabwa, Jan Maes, Sebastian Munck, Roger Busson, Jef Rozenski, Camila V Esguerra, Peter A M de Witte
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/71b687a0d6fe430fac940e3f9ada55c7
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