Genetic variants of programmed cell death 1 are associated with HBV infection and liver disease progression

Abstract The inhibitory effects of programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) modulates T-cell depletion. T-cell depletion is one of the key mechanisms of hepatitis B virus (HBV) persistence, in particular liver disease progression and the development of hepatocellular carci...

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Main Authors: Nghiem Xuan Hoan, Pham Thi Minh Huyen, Mai Thanh Binh, Ngo Tat Trung, Dao Phuong Giang, Bui Thuy Linh, Dang Thi Ngoc Dung, Srinivas Reddy Pallerla, Peter G. Kremsner, Thirumalaisamy P. Velavan, Mai Hong Bang, Le Huu Song
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/71be686ae0ba4298b28c563a77522a3e
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