The NF-κB Transcription Factor c-Rel Modulates Group 2 Innate Lymphoid Cell Effector Functions and Drives Allergic Airway Inflammation

The NF-κB Transcription Factor c-Rel Modulates Group 2 Innate Lymphoid Cell Effector Functions and Drives Allergic Airway Inflammation

Group 2 innate lymphoid cells (ILC2s) play a key role in the initiation and orchestration of early type 2 immune responses. Upon tissue damage, ILC2s are activated by alarmins such as IL-33 and rapidly secrete large amounts of type 2 signature cytokines. ILC2 activation is governed by a network of t...

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Autores principales: Barbara C. Mindt, Sai Sakktee Krisna, Claudia U. Duerr, Mathieu Mancini, Lara Richer, Silvia M. Vidal, Steven Gerondakis, David Langlais, Jörg H. Fritz
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
group 2 innate lymphoid cell (ILC2)
IL-33
c-Rel
type 2 immunity
airway inflammation
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/71c35d55ad3341a481a892ff468e1673
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https://doaj.org/article/71c35d55ad3341a481a892ff468e1673

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