PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

ABSTRACT Stimulator of interferon genes (STING) is an essential adaptor protein of the innate DNA-sensing signaling pathway, which recognizes genomic DNA from invading pathogens to establish antiviral responses in host cells. STING activity is tightly regulated by several posttranslational modificat...

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Auteurs principaux: Guoxin Ni, Zhe Ma, Jason P. Wong, Zhigang Zhang, Emily Cousins, M. Ben Major, Blossom Damania
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/71d62a9b3f424400bb4401a17454e0b3
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