NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region

NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region

The mechanisms underlying specific TSS selection in mammals remain unclear. Here the authors show that the ubiquitously expressed transcription factor NF-Y regulate fidelity of transcription initiation at gene promoters, maintaining the region upstream of TSSs in a nucleosome-depleted state, while p...

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Autores principales: Andrew J. Oldfield, Telmo Henriques, Dhirendra Kumar, Adam B. Burkholder, Senthilkumar Cinghu, Damien Paulet, Brian D. Bennett, Pengyi Yang, Benjamin S. Scruggs, Christopher A. Lavender, Eric Rivals, Karen Adelman, Raja Jothi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/71e2bfa890304bdaa5931f07b5e2e8a9
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https://doaj.org/article/71e2bfa890304bdaa5931f07b5e2e8a9

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