NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region

The mechanisms underlying specific TSS selection in mammals remain unclear. Here the authors show that the ubiquitously expressed transcription factor NF-Y regulate fidelity of transcription initiation at gene promoters, maintaining the region upstream of TSSs in a nucleosome-depleted state, while p...

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Bibliographic Details
Main Authors: Andrew J. Oldfield, Telmo Henriques, Dhirendra Kumar, Adam B. Burkholder, Senthilkumar Cinghu, Damien Paulet, Brian D. Bennett, Pengyi Yang, Benjamin S. Scruggs, Christopher A. Lavender, Eric Rivals, Karen Adelman, Raja Jothi
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/71e2bfa890304bdaa5931f07b5e2e8a9
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