NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region
The mechanisms underlying specific TSS selection in mammals remain unclear. Here the authors show that the ubiquitously expressed transcription factor NF-Y regulate fidelity of transcription initiation at gene promoters, maintaining the region upstream of TSSs in a nucleosome-depleted state, while p...
Saved in:
Main Authors: | Andrew J. Oldfield, Telmo Henriques, Dhirendra Kumar, Adam B. Burkholder, Senthilkumar Cinghu, Damien Paulet, Brian D. Bennett, Pengyi Yang, Benjamin S. Scruggs, Christopher A. Lavender, Eric Rivals, Karen Adelman, Raja Jothi |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/71e2bfa890304bdaa5931f07b5e2e8a9 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Origin Replication Complex Binding, Nucleosome Depletion Patterns, and a Primary Sequence Motif Can Predict Origins of Replication in a Genome with Epigenetic Centromeres
by: Hung-Ji Tsai, et al.
Published: (2014) -
The biogenesis and function of nucleosome arrays
by: Ashish Kumar Singh, et al.
Published: (2021) -
Multivalent engagement of TFIID to nucleosomes.
by: Rick van Nuland, et al.
Published: (2013) -
Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions
by: Stephen E. Farr, et al.
Published: (2021) -
Mechanisms of Nucleosome Reorganization by PARP1
by: Natalya V. Maluchenko, et al.
Published: (2021)