NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region
The mechanisms underlying specific TSS selection in mammals remain unclear. Here the authors show that the ubiquitously expressed transcription factor NF-Y regulate fidelity of transcription initiation at gene promoters, maintaining the region upstream of TSSs in a nucleosome-depleted state, while p...
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Auteurs principaux: | Andrew J. Oldfield, Telmo Henriques, Dhirendra Kumar, Adam B. Burkholder, Senthilkumar Cinghu, Damien Paulet, Brian D. Bennett, Pengyi Yang, Benjamin S. Scruggs, Christopher A. Lavender, Eric Rivals, Karen Adelman, Raja Jothi |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/71e2bfa890304bdaa5931f07b5e2e8a9 |
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