Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit

The authors describe a vesicular transporter, VST-1, that is required in glutamatergic chemosensory neurons for chemotactic avoidance behavior in C. elegans. VST-1 antagonizes VGLUT-dependent packaging of glutamate into synaptic vesicles and determines the strength of synaptic glutamate signaling.

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Autores principales: Jung-Hwan Choi, Lauren Bayer Horowitz, Niels Ringstad
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/71f5fa8469e243af857066a87c96ff64
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