Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation

Striatal D1 and D2-receptor expressing neurons have been shown to have opposing effects on reward-related behaviours. Here the authors reveal that specific activation of both D1 and D2 neurons in the nucleus accumbens leads to increase in motivational drive in rodents.

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Autores principales: Carina Soares-Cunha, Barbara Coimbra, Ana David-Pereira, Sonia Borges, Luisa Pinto, Patricio Costa, Nuno Sousa, Ana J. Rodrigues
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/721a714360be48318e60869c945a36b4
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