Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation

Striatal D1 and D2-receptor expressing neurons have been shown to have opposing effects on reward-related behaviours. Here the authors reveal that specific activation of both D1 and D2 neurons in the nucleus accumbens leads to increase in motivational drive in rodents.

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Autores principales:	Carina Soares-Cunha, Barbara Coimbra, Ana David-Pereira, Sonia Borges, Luisa Pinto, Patricio Costa, Nuno Sousa, Ana J. Rodrigues
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/721a714360be48318e60869c945a36b4
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spelling	oai:doaj.org-article:721a714360be48318e60869c945a36b42021-12-02T15:35:46ZActivation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation10.1038/ncomms118292041-1723https://doaj.org/article/721a714360be48318e60869c945a36b42016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11829https://doaj.org/toc/2041-1723Striatal D1 and D2-receptor expressing neurons have been shown to have opposing effects on reward-related behaviours. Here the authors reveal that specific activation of both D1 and D2 neurons in the nucleus accumbens leads to increase in motivational drive in rodents.Carina Soares-CunhaBarbara CoimbraAna David-PereiraSonia BorgesLuisa PintoPatricio CostaNuno SousaAna J. RodriguesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carina Soares-Cunha Barbara Coimbra Ana David-Pereira Sonia Borges Luisa Pinto Patricio Costa Nuno Sousa Ana J. Rodrigues Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
description	Striatal D1 and D2-receptor expressing neurons have been shown to have opposing effects on reward-related behaviours. Here the authors reveal that specific activation of both D1 and D2 neurons in the nucleus accumbens leads to increase in motivational drive in rodents.
format	article
author	Carina Soares-Cunha Barbara Coimbra Ana David-Pereira Sonia Borges Luisa Pinto Patricio Costa Nuno Sousa Ana J. Rodrigues
author_facet	Carina Soares-Cunha Barbara Coimbra Ana David-Pereira Sonia Borges Luisa Pinto Patricio Costa Nuno Sousa Ana J. Rodrigues
author_sort	Carina Soares-Cunha
title	Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
title_short	Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
title_full	Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
title_fullStr	Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
title_full_unstemmed	Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
title_sort	activation of d2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/721a714360be48318e60869c945a36b4
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Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation

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