A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins

ABSTRACT Cell-autonomous immunity relies on the rapid detection of invasive pathogens by host proteins. Guanylate binding proteins (GBPs) have emerged as key mediators of vertebrate immune defense through their ability to recognize a diverse array of intracellular pathogens and pathogen-containing c...

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Bibliographic Details
Main Authors: Kristin M. Kohler, Miriam Kutsch, Anthony S. Piro, Graham D. Wallace, Jörn Coers, Matthew F. Barber
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/721fbbdb05764fda8e3d02eb4fe03d8b
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