Gene expression signature of normal cell-of-origin predicts ovarian tumor outcomes.

The potential role of the cell-of-origin in determining the tumor phenotype has been raised, but not adequately examined. We hypothesized that distinct cells-of-origin may play a role in determining ovarian tumor phenotype and outcome. Here we describe a new cell culture medium for in vitro culture...

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Autores principales: Melissa A Merritt, Stefan Bentink, Matthew Schwede, Marcin P Iwanicki, John Quackenbush, Terri Woo, Elin S Agoston, Ferenc Reinhardt, Christopher P Crum, Ross S Berkowitz, Samuel C Mok, Abigail E Witt, Michelle A Jones, Bin Wang, Tan A Ince
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/72352486e23d439e8ed96457071ba73e
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