Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation
The polycomb repressor protein Bmi1 has a role in self-renewal and tumorigenesis. Here, the authors use lineage tracing to show that Bmi-expressing cells are a distinct population of cells, primarily found in the luminal compartment, which is castration resistant, can initiate cancer and regenerate...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2016
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/723bb9021c454c7c895f31deacc88d0a |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|