Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the <named-content content-type="genus-species">Candida albicans</named-content> Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling

Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the <named-content content-type="genus-species">Candida albicans</named-content> Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling

ABSTRACT Organisms must adapt to changes in oxygen tension if they are to exploit the energetic benefits of reducing oxygen while minimizing the potentially damaging effects of oxidation. Consequently, organisms in all eukaryotic kingdoms display robust adaptation to hypoxia (low oxygen levels). Thi...

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Bibliographic Details
Main Authors: Arnab Pradhan, Gabriela M. Avelar, Judith M. Bain, Delma S. Childers, Daniel E. Larcombe, Mihai G. Netea, Elena Shekhova, Carol A. Munro, Gordon D. Brown, Lars P. Erwig, Neil A. R. Gow, Alistair J. P. Brown
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
hypoxia
Candida albicans
cell wall
β-glucan masking
mitochondrial signaling
cAMP-protein kinase A signaling
Microbiology
QR1-502
Online Access:https://doaj.org/article/7246d978081d4c2eaaefcf2803e7a1d6
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