Activation of (pro)renin by (pro)renin receptor in extracellular vesicles from osteoclasts
Abstract The (pro)renin receptor (PRR) is a multifunctional integral membrane protein that serves as a component of the vacuolar H+-ATPase (V-ATPase) and also activates (pro)renin. We recently showed that full-length PRR, found as part of a V-ATPase sub-complex, is abundant in extracellular vesicles...
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Main Authors: | Jonathan B. Murray, Christy Mikhael, Guanghong Han, Lorraine Perciliano de Faria, Wellington J. Rody, L. Shannon Holliday |
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Format: | article |
Language: | EN |
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Nature Portfolio
2021
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Online Access: | https://doaj.org/article/726b5d06cd4c4dac8379069a60fd4cb3 |
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