Next-generation sequence analysis of cancer xenograft models.

Next-generation sequence analysis of cancer xenograft models.

Next-generation sequencing (NGS) studies in cancer are limited by the amount, quality and purity of tissue samples. In this situation, primary xenografts have proven useful preclinical models. However, the presence of mouse-derived stromal cells represents a technical challenge to their use in NGS s...

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Bibliographic Details
Main Authors: Fernando J Rossello, Richard W Tothill, Kara Britt, Kieren D Marini, Jeanette Falzon, David M Thomas, Craig D Peacock, Luigi Marchionni, Jason Li, Samara Bennett, Erwin Tantoso, Tracey Brown, Philip Chan, Luciano G Martelotto, D Neil Watkins
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/728a70be11b74d5e9bfec58d72aeeeed
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https://doaj.org/article/728a70be11b74d5e9bfec58d72aeeeed

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