Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance

High-resolution cryo-EM structures and biochemical analyses of the human mitoribosome, in complex with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight into mechanisms of mitoribosome recycling and resistance to antibiotic fusidic acid.

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Auteurs principaux: Ravi Kiran Koripella, Ayush Deep, Ekansh K. Agrawal, Pooja Keshavan, Nilesh K. Banavali, Rajendra K. Agrawal
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/72b116d70c9243d7a6170b9fd638970d
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