Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance

High-resolution cryo-EM structures and biochemical analyses of the human mitoribosome, in complex with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight into mechanisms of mitoribosome recycling and resistance to antibiotic fusidic acid.

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Autores principales:	Ravi Kiran Koripella, Ayush Deep, Ekansh K. Agrawal, Pooja Keshavan, Nilesh K. Banavali, Rajendra K. Agrawal
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/72b116d70c9243d7a6170b9fd638970d
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spelling	oai:doaj.org-article:72b116d70c9243d7a6170b9fd638970d2021-12-02T17:40:23ZDistinct mechanisms of the human mitoribosome recycling and antibiotic resistance10.1038/s41467-021-23726-42041-1723https://doaj.org/article/72b116d70c9243d7a6170b9fd638970d2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23726-4https://doaj.org/toc/2041-1723High-resolution cryo-EM structures and biochemical analyses of the human mitoribosome, in complex with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight into mechanisms of mitoribosome recycling and resistance to antibiotic fusidic acid.Ravi Kiran KoripellaAyush DeepEkansh K. AgrawalPooja KeshavanNilesh K. BanavaliRajendra K. AgrawalNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ravi Kiran Koripella Ayush Deep Ekansh K. Agrawal Pooja Keshavan Nilesh K. Banavali Rajendra K. Agrawal Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
description	High-resolution cryo-EM structures and biochemical analyses of the human mitoribosome, in complex with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight into mechanisms of mitoribosome recycling and resistance to antibiotic fusidic acid.
format	article
author	Ravi Kiran Koripella Ayush Deep Ekansh K. Agrawal Pooja Keshavan Nilesh K. Banavali Rajendra K. Agrawal
author_facet	Ravi Kiran Koripella Ayush Deep Ekansh K. Agrawal Pooja Keshavan Nilesh K. Banavali Rajendra K. Agrawal
author_sort	Ravi Kiran Koripella
title	Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
title_short	Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
title_full	Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
title_fullStr	Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
title_full_unstemmed	Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
title_sort	distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/72b116d70c9243d7a6170b9fd638970d
work_keys_str_mv	AT ravikirankoripella distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT ayushdeep distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT ekanshkagrawal distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT poojakeshavan distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT nileshkbanavali distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT rajendrakagrawal distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance
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Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance

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