Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
High-resolution cryo-EM structures and biochemical analyses of the human mitoribosome, in complex with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight into mechanisms of mitoribosome recycling and resistance to antibiotic fusidic acid.
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Nature Portfolio
2021
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oai:doaj.org-article:72b116d70c9243d7a6170b9fd638970d2021-12-02T17:40:23ZDistinct mechanisms of the human mitoribosome recycling and antibiotic resistance10.1038/s41467-021-23726-42041-1723https://doaj.org/article/72b116d70c9243d7a6170b9fd638970d2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23726-4https://doaj.org/toc/2041-1723High-resolution cryo-EM structures and biochemical analyses of the human mitoribosome, in complex with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight into mechanisms of mitoribosome recycling and resistance to antibiotic fusidic acid.Ravi Kiran KoripellaAyush DeepEkansh K. AgrawalPooja KeshavanNilesh K. BanavaliRajendra K. AgrawalNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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DOAJ |
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DOAJ |
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Science Q |
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Science Q Ravi Kiran Koripella Ayush Deep Ekansh K. Agrawal Pooja Keshavan Nilesh K. Banavali Rajendra K. Agrawal Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance |
| description |
High-resolution cryo-EM structures and biochemical analyses of the human mitoribosome, in complex with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight into mechanisms of mitoribosome recycling and resistance to antibiotic fusidic acid. |
| format |
article |
| author |
Ravi Kiran Koripella Ayush Deep Ekansh K. Agrawal Pooja Keshavan Nilesh K. Banavali Rajendra K. Agrawal |
| author_facet |
Ravi Kiran Koripella Ayush Deep Ekansh K. Agrawal Pooja Keshavan Nilesh K. Banavali Rajendra K. Agrawal |
| author_sort |
Ravi Kiran Koripella |
| title |
Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance |
| title_short |
Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance |
| title_full |
Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance |
| title_fullStr |
Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance |
| title_full_unstemmed |
Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance |
| title_sort |
distinct mechanisms of the human mitoribosome recycling and antibiotic resistance |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/72b116d70c9243d7a6170b9fd638970d |
| work_keys_str_mv |
AT ravikirankoripella distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT ayushdeep distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT ekanshkagrawal distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT poojakeshavan distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT nileshkbanavali distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance AT rajendrakagrawal distinctmechanismsofthehumanmitoribosomerecyclingandantibioticresistance |
| _version_ |
1718379770168737792 |